Open access
Jul 2026
The CAFs-derived YAP1-periostin axis forms a fibrotic tumor microenvironment to promote metastatic lung tumor growth
A CD248–YAP1-Periostin-ITGB1 axis that contributes to a prometastatic feedback loop in NSCLC is suggested, indicating that focusing on this axis may be a viable therapeutic approach to prevent NSCLC metastasis.
Jie-Heng Wu, Xuan-Yin Wang, Ze-Yang Yang et al.
· Journal of Translational Med... · 0 citations