Catalytic asymmetric reactions of isoxazole derivatives: organocatalysis, metal catalysis and phase-transfer catalysis.
Isoxazoles are versatile N,O-containing five-membered heterocyclic building blocks widely utilized in the construction of chiral pharmaceutical intermediates. Over the past two decades, tremendous progress has been made in their catalytic asymmetric transformations, which can be categorized into three types: organocata...