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Author

Lu-Ying Pei

2 papers indexed here

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Open access Sep 2026

A high-throughput compound screen identifies multiple druggable targets in Plasmodium falciparum transmission stages

Most antimalarials are ineffective against the sexual transmission stages, known as gametocytes, of the malaria parasite Plasmodium falciparum. Their low sensitivity to drugs is attributed to limited compound uptake and a poorly understood form of cellular quiescence. Our current understanding of druggable transmission...

Leonie Seefeldt, Christin Gumpp, O. Carril et al. · 0 citations
Open access Oct 2026

Screening of a chemogenetic library unveils dual-stage antiplasmodials with low cytotoxicity

ABSTRACT The global effort to eradicate malaria requires the development of drugs with novel mechanisms of action and differentiated pharmacological profiles. Both liver and blood phases of Plasmodium infection are essential for disease progression and transmission, making them primary targets for pharmacological inter...

Laura Torres, Matthew E. Fishbaugher, Mélanie Lam et al. · 0 citations

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