Polystyrene nanoplastics enhance lead-induced ferroptosis in HT22 cells via clathrin-mediated endocytosis.
The co-occurrence of nanoplastics and heavy metals like lead (Pb) in the environment presents a significant neurotoxic risk, yet the mechanistic basis for their combined effects remains poorly defined. In this study, we investigated the combined neurotoxic effects of 50nm polystyrene nanoplastics (PS-NPs) and Pb in mou...