Neutrophil extracellular traps promote glomerular endothelial injury in IgA nephropathy via the cGAS-STING pathway.
IgA nephropathy (IgAN), a common primary glomerulonephritis, has an incompletely elucidated pathogenesis. Neutrophil extracellular traps (NETs), key components of innate immunity, are known to mediate renal injury in various kidney diseases, yet their role in IgAN remains unclear. In this study, we observed significant...