Open access
Oct 2026
A common germline 3′ UTR variant controls DDIT4 translation efficiency and stress responses in cancer cells
A pipeline to identify translation-associated single-nucleotide polymorphisms (tranSNPs) by integrating analysis of total and polysome-associated mRNAs is developed and extensively validate, revealing an association between rs1053639 genotype and clinical outcome in colorectal cancer.
M. Hamadou, Laura Alunno, Tecla Venturelli et al.
· iScience · 1 citation