Open access
Jul 2026
Context-dependent YEATS-domain inhibition enhances neuronal resilience and improves ALS phenotypes.
The role of the ENL/AF9 YEATS domain is defined using complementary chemical and genetic perturbations and established ENL/AF9 YEATS-domain inhibition as a context-dependent strategy to enhance neuronal resilience with relevance to ALS and related proteotoxic disorders.
Luca Piccolo, Chansunee Panto, Ranchana Yeewa et al.
· Neurobiology of Disease · 1 citation