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Lucas A. Meirelles

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Review Open access Sep 2026

Simulating the host niche: balancing complexity and control in the experimental evolution of antibiotic resistance and pathoadaptation

Abstract The ‘ESKAPE’ pathogens cause the majority of antibiotic-resistant infections in humans, with associated mortality expected to surpass that of cancer by 2050. Outbreak strains of these pathogens often demonstrate a remarkable ability to establish infection and easily acquire novel antimicrobial resistance mecha...

Juan Hernandez-Bird, Lucas A. Meirelles · 0 citations

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