Lucas Rafael Pereira Camara

Organelle-specific crosstalk between calcium and redox signaling in pancreatic β-cells in physiology and type 2 diabetes

Two of the main intracellular signaling molecules in pancreatic β-cells are calcium (Ca2+) and reactive oxygen species (ROS). Ca2+ signaling is essential for regulating energy metabolism, insulin secretion, and the modulation of key factors involved in β-cell survival and function. In parallel, redox signaling also aff...