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Author

Lucía Cañizares-Moscato

2 papers indexed here

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Review Open access Sep 2026

Beyond Bulk: Cell‐Type‐Resolved Epigenomics as the Path Forward in Alzheimer's Disease Research

Alzheimer's disease (AD) is a complex neurodegenerative disorder in which most risk variants are noncoding and are enriched at gene regulatory regions, implicating epigenetic mechanisms as central mediators of disease pathogenesis. For most of the history of AD epigenetics research, bulk tissue analysis has dominated,...

Lucía Cañizares-Moscato, Jose Ruiz-Iglesias, J. Isoler-Alcaraz et al. · 0 citations
Open access Aug 2026

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

ABSTRACT Living cell therapies lack robust, reversible mechanisms for externally controlling therapeutic activity after administration, limiting their safety and clinical adaptability. Here we engineer a drug‐gated cellular immunotherapy platform in which T cells function as programmable factories that secrete two inac...

S. Luengo-Arias, Carmen Domínguez-Alonso, Ivana Zagorac et al. · 0 citations

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