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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Lucía López-Pacios

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Open access Oct 2026

Function-preserving photooxidation of AS1411 aptamer by a G-quadruplex-guided photosensitizer

AS1411 is a G-quadruplex (G4) aptamer that binds nucleolin (NCL) and is widely used to promote cancer-associated delivery of photoactive cargos. Yet the fate of AS1411 after photosensitizer loading and light activation remains unclear as reactive oxygen species (ROS) generation could disrupt its guanine-rich fold and a...

Maria V. Cottini, Karolina Saczuk, Jakub Trojnar et al. · 0 citations

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