Author

Lucie Nepovímová

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Open access Jul 2026

Structures of asymmetric particles of tick-borne encephalitis virus provide insight into flavivirus assembly and maturation

It is shown that many particles of tick-borne encephalitis virus (TBEV) are asymmetric and lack subsets of surface heterodimers, explaining how flaviviruses can be neutralized by antibodies that bind to regions of E proteins normally inaccessible in the spiky or herringbone structures.

Tibor Füzik, Maria Anastasina, Peter Pajtinka et al. · Science Advances · 0 citations