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Author

Lucy M. Fitzgibbons

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Open access Sep 2026

Emerging Roles of TMEM97/Sigma-2 Receptor in Breast Cancer Endocrine Resistance: Links to mTOR Signaling and Cholesterol Metabolism

Breast cancer remains one of the most common cancers in women, in which the majority of cases exhibit a hormone receptor-positive subtype. Although several treatment options are available for patients with this subtype, first-line therapies mainly rely on the patient’s sensitivity to endocrine therapy. Therapy resistan...

Lucy M. Fitzgibbons, Yuan-Qin Zhang, Xiang-Wei Fang et al. · 0 citations

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