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Ludwig Aigner

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Aug 2026

Vesicostomy in the Rat Model for Low-Pressure Urinary Drainage in Neurogenic Bladder Research.

The rat is the primary animal model for preclinical research on spinal cord injury (SCI)-induced neurogenic lower urinary tract dysfunction (nLUTD). Owing to its anatomical and functional similarity to humans, rats closely recapitulate key pathological consequences of SCI. However, a crucial translational gap remains:...

Martha Georgina Brandtner, E. Beyerer, Michael Kleindorfer et al. · 0 citations
Open access Sep 2026

Modulating Secondary Inflammation After Spinal Cord Injury Affects Pathological Bladder Remodeling

Purpose Neurogenic lower urinary tract dysfunction (nLUTD) develops in nearly all patients after spinal cord injury (SCI). Evolving neuroinflammation is considered a key driver of secondary injury and is associated with worsening outcomes. However, few studies have examined treatments for nLUTD after SCI that specifica...

Michael Kleindorfer, K. Roider, K. Monastyrskaia et al. · 0 citations
Review Open access Aug 2026

Disentangling the role of adaptive immunity in Alzheimer’s disease

Alzheimer’s disease (AD), the most common age-related neurodegenerative disorder, is characterized by progressive synaptic and neuronal loss, amyloid-β deposition, hyperphosphorylated tau accumulation, and chronic neuroinflammation, traditionally attributed primarily to the innate immune system. Increasing evidence,...

Marco Zattoni, Ludwig Aigner · 0 citations

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