Functional characterization of GplA (MSMEG-0394) reveals a novel determinant of glycopeptidolipids homeostasis in Mycobacterium smegmatis
Introduction Glycopeptidolipids (GPLs) are major constituents of the cell envelope of non-tuberculous mycobacteria (NTM) and play essential roles in colony morphology, surface motility, biofilm formation, antimicrobial susceptibility, and host–pathogen interactions. Although the GPL biosynthetic locus has been extensiv...