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Author

Luiz Costa

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3 papers indexed here

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Open access Sep 2026

Cognitive psychiatry of mediumship: A genetic, neuroconnectomic, interhemispheric, and psychofunctional hypothesis of brain organization in mediums

Mediumship is a complex human phenomenon that can be investigated by cognitive psychiatry and consciousness neuroscience without theological assumptions or psychopathological reductionism. This study aimed to formulate and theoretically substantiate a neuroconnectomic, genetic, and psychofunctional hypothesis of medium...

João Acyr Chueiry, Giovanna Azevedo Rodrigues, Luiz Costa et al. · 0 citations
Review Open access Sep 2026

Haloperidol as a Novel Augmentation Strategy in Treatment-Resistant Depression: A Clinical Practice Perspective with Case Series

Treatment-resistant depression (TRD) remains a major clinical challenge when adequate antidepressant trials fail to achieve remission. This clinical practice perspective examines low-dose haloperidol as a potential augmentation strategy in carefully selected, treatment-refractory affective presentations. The manuscript...

Giovanna Azevedo Rodrigues, Fernando Martins Castanheira, Luiz Costa et al. · 0 citations
Review Open access Aug 2026

The General Psychiatric Syndrome as a Transdiagnostic Hypothesis: A Critical Appraisal of Evidence, Interpretation and Clinical Reach

Persistent comorbidity, diagnostic instability and the scarcity of disorder-specific causes have encouraged the proposal that a single superordinate dimension underlies liability to all common mental disorders. This proposition, expressed empirically as the general factor of psychopathology and framed conceptually as a...

Luiz Costa, Fernando Martins Castanheira, Giovanna Azevedo Rodrigues et al. · 1 citation

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