Lukas Ernst

The ABCG transporter OsPDR17 mediates transport of 5,10-diketo-casbene and enhances disease resistance in rice.

Compound 5,10-diketo-casbene (DKC) is a key macrocyclic diterpenoid phytoalexin contributing to rice resistance against bacterial blight. Although its activity depends on transmembrane transport, the transporter of DKC remains unknown. Using transcriptome profiling and a yeast expression system, OsPDR17, an ABCG transp...