Author

Lulu Liu

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Open access Jul 2026

A synthetic virus-like assembly unlocks dual-antigen presentation for broad-spectrum anti-SARS-CoV-2 immunity

This characterized virion-mimetic structural vaccine not only induces the production of high-efficiency antibodies against both the spike and N proteins but also elicits robust S1-specific and N-specific CTL responses in animal models, creating an optimal microenvironment for eliciting potent and broad-spectrum adaptive immune responses.

Jingjing Zhang, Fen Zeng, Yanmei Li et al. · Scientific Reports · 0 citations

Open access Jul 2026

Integrating AlphaFold2 with physics-based ensemble docking for high-efficiency nanobody discovery

A computational framework that progressed from next-generation sequencing (NGS)derived candidate nanobody sequences to predicted structures using AlphaFold2, and prioritized nanobodies based on predicted binding energy scores supported the practical utility of the framework for enriching functional nanobodies from experimentally pre-enriched NGS-derived pools.

Yinghao Guo, Renfang Guan, Lunde Jin et al. · Chemical Science · 0 citations