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Open access Sep 2026

Nasal Exposure to Environmental PM2.5 Drives Testicular Pyroptosis and Tissue Damage: Evidence from Inhibitor Intervention and Multi Source Data

Exposure to PM2.5 from vehicle exhaust impairs male reproductive function and the pyroptosis inhibitor protects reproductive function by suppressing the NLRP3/Caspase-1 signaling pathway, thereby promoting an inflammatory interaction network that contributes to systemic inflammation.

Luo Yi, Wan-Ang Cao, Ma Hong · 0 citations

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