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Author

Lynn A. Spruce

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Open access Oct 2026

Adding Tat-Beclin1 to an endurance training program promotes additive improvements in physical function in aged male mice.

Autophagy is a hallmark of aging, but it has not been exclusively targeted to attenuate aging-related physical dysfunction. Here, we combined Tat-Beclin1 and endurance training to determine its effect on physical function domains in aged male mice. Mice were randomly divided into Control (N = 5), Tat-Beclin1 (TB, 15 mg...

T. Tchen, Shakibur Rahman, T. Ghiarone et al. · 0 citations
Open access Jul 2026

HLA-Shuttle: A system for enhancing antigen presentation in immunologically cold tumors 2258016

HLA-Shuttle restores antigen presentation in immunologically cold tumor cells, facilitating identification of TAAs with favorable therapeutic potential and identifying multiple novel tumor associated antigens (TAAs) from both known and novel cancer immunotherapy targets.

Daniel Hwang, Molly C. Erdman, Santosh Adhikari et al. · 0 citations

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