EXPRESS: Circular RNAs as Next Generation Biomarkers for Minimal Residual Disease: Mechanistic Insights and Clinical Translation.
Minimal residual disease (MRD) denotes the persistence of malignant cells below the detection limits of conventional diagnostics and is a principal determinant of relapse and therapeutic failure. Enhancing MRD detection is therefore essential for precision oncology. Tumor‑derived circular RNAs (circRNAs)-covalently clo...