M. Abosaoda

Mitochondria-Centered Metabolic Microdomains: Regulatory Roles in Synaptic Plasticity and Circuit Homeostasis.

The metabolism of neuronal activity is highly localized and cannot be sustained by cell-wide distribution of energy. Neurons and glia organize metabolic enzymes, mitochondria, lipid droplets, and endoplasmic reticulum (ER) contacts into spatially localized microdomains that dynamically couple energy generation to synap...