Author

M. Andreola

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Review Open access Sep 2026

Medicinal Chemistry Aspects of Thiazole and Thiazolidine Derivatives as Fundamental Building Blocks to Design New NNRTIs Against HIV‐1 Reverse Transcriptase

The therapy to treat the Human Immunodeficiency virus (HIV) and decrease the viral load has been a challenge since its discovery due to its ability to mutate, escape from drug therapies, and immunologic system. Consequently, the development of new therapies, especially potential molecules that focus on specific viral m...

José Arion da Silva Moura, Matheus Frota Guimarães de Melo, Diane Regis Santos Do Nascimento et al. · ChemMedChem · 0 citations

Open access Jul 2026

Dibenzoacridinium derivatives: a new class of G-quadruplex ligands with anti-HIV-1 properties

The design, synthesis, and biophysical characterization of a novel class of G4-stabilizing ligands based on a positively charged dibenzoacridinium (DBA) core are reported, identifying DBAs as a new class of G-quadruplex ligands with anti-HIV properties.

Aman Kabbara, C. Buré, A. Guédin et al. · RSC Medicinal Chemistry · 0 citations