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Review Open access Oct 2026

Immunotherapy and circulating tumor DNA in HPV-positive oropharyngeal cancer: a systematic review and exploratory meta-analysis of survival and surveillance outcomes.

BACKGROUND Human papillomavirus-positive oropharyngeal squamous cell carcinoma is biologically distinct, yet the effect of immune checkpoint inhibition and the performance of circulating tumor DNA (ctDNA) as a biomarker remain undefined. METHODS We searched databases through October 2025 for prospective studies of ad...

M. Aouf, László Tamás, Hussein A. El-Shirbeny et al. · 0 citations

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