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M. Attwa

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Open access Sep 2026

An Ultra‐Fast UPLC‐MS/MS Method for Quantifying Ivosidenib: Application to Assessment of Metabolic Stability in Human Liver Microsomes

Ivosidenib (Tibsovo) is a groundbreaking, first‐in‐class medication that specifically and reversibly blocks isocitrate dehydrogenase (IDH1), earning multiple FDA approvals for cancers harboring IDH1 mutations. This research developed a rapid, dependable, and sensitive UPLC‐MS/MS technique to assess the metabolic stabil...

M. Attwa, A. Abdelhameed, H. Alrabiah et al. · 0 citations

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