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M. Barros

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Preprint Oct 2026

From communication to computation in neurons-on-a-chip: an in silico study of neurotopomorphic computing

Living neuronal networks transform inputs through recurrent cellular and population dynamics, yet it is unknown which network architecture supports which computation. Neurons-on-a-chip turn this question into a design problem because microchannels guide axonal growth and set the network architecture. We introduce IC$^3...

M. Barros · 0 citations
Open access 2026

Topology-Dependent Communication and Computing in Bioengineered Neuronal Networks

Bioengineered neuronal systems are increasingly explored as living computational substrates, yet their end-to-end communication properties remain poorly characterized beyond global activity statistics. We model a mechanosensitive spiking neuronal network as a noisy multiple-input multiple-output (MIMO) communication sy...

Joshua Mullett, A. Mohr, R. Scherer et al. · 2 citations

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