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M. Bartolini

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Open access Aug 2026

The role of circulating tumor DNA (ctDNA) to detect minimal residual disease in locally advanced gastroesophageal carcinoma: the BUTTERFLY study

Background Despite advances in perioperative and neoadjuvant strategies, patients with locally advanced gastroesophageal cancers remain at high risk of recurrence after curative intent treatment. No validated biomarkers are available to detect minimal residual disease (MRD) or to guide post-operative risk-adapted manag...

A. Puccini, L. Paracchini, R. Alfieri et al. · 0 citations
Review Sep 2026

Long non-coding RNAs in colorectal cancer: shaping the tumour microenvironment and advancing precision oncology.

This Review explores the dual roles of lncRNAs as oncogenes or tumour suppressors, their involvement in immune modulation, vascular remodelling and extracellular matrix dynamics, and their involvement in immune modulation, vascular remodelling and extracellular matrix dynamics.

M. Bartolini, F. Battaglin, S. Soni et al. · 0 citations
Review Open access Jul 2026

Next-generation precision oncology in microsatellite stable colorectal cancer: integrated targeting beyond RAS and RAF

Integrated, multidimensional biomarker approaches and artificial intelligence-driven interpretation of tumor and TME features are expected to guide personalized therapy, anticipate resistance, and broaden the benefit of targeted and immune-based interventions in CRC.

M. Bartolini, S. Algaze, H. Lenz · 0 citations

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