Background Despite advances in perioperative and neoadjuvant strategies, patients with locally advanced gastroesophageal cancers remain at high risk of recurrence after curative intent treatment. No validated biomarkers are available to detect minimal residual disease (MRD) or to guide post-operative risk-adapted manag...
A. Puccini, L. Paracchini, R. Alfieri et al.· ESMO gastrointestinal oncolo...· 0 citations
This Review explores the dual roles of lncRNAs as oncogenes or tumour suppressors, their involvement in immune modulation, vascular remodelling and extracellular matrix dynamics, and their involvement in immune modulation, vascular remodelling and extracellular matrix dynamics.
M. Bartolini, F. Battaglin, S. Soni et al.· Nature reviews: Gastroentero...· 0 citations
Integrated, multidimensional biomarker approaches and artificial intelligence-driven interpretation of tumor and TME features are expected to guide personalized therapy, anticipate resistance, and broaden the benefit of targeted and immune-based interventions in CRC.
M. Bartolini, S. Algaze, H. Lenz· ESMO Open· 0 citations
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