Review
Open access
Oct 2026
The CXCL12/CXCR4 axis in breast cancer-associated fibroblasts: a transcriptome analysis and systematic literature review
It is hypothesised that the CXCR4 High -CAF transcriptome profile is compatible with a biologically plausible theory of transition between paracrine and autocrine regulatory modes and inflammatory cell states, and suggests a possible shift from TGF-β-dependent to CXCR4-mediated regulation of CXCL12.
Sergey Vladimirov, David Sergeevichev, M. Bogachek et al.
· Frontiers in Bioengineering... · 0 citations