Open access
Oct 2026
PIEZO1 Is a Contextual Mechanosensor and Its Depletion in Scx‐Lineage Cells Accelerates Structural and Functional Recovery
Findings reveal a context‐dependent role for PIEZO1 in tendon biology: while PIEZO1 supports mechanosensing and adaptation in mature tendon, it enables wound‐site recruitment of Scx+ fibroblast populations that impair healing after injury.
Nicole A. Chittim, M. Wolleb, M. Greenwald et al.
· The FASEB Journal · 0 citations