Author

M. Bonfanti

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Open access Sep 2026

Stem cell morphology defines functional heterogeneity and therapeutic vulnerabilities in glioblastoma.

BACKGROUND Glioblastoma (GBM) is an aggressive brain tumor and an unmet clinical need due to its invasiveness and therapy resistance. These features are driven by glioblastoma stem-like cells (GSLCs), which exhibit remarkable functional heterogeneity. While transcriptional profiling has helped define this heterogeneity...

C. Barelli, M. Bonfanti, F. Mirabella et al. · Neuro-Oncology · 0 citations

Open access Aug 2026

The human RNA-DNA interactome is cell type-specific and dynamic

The RNA-DNA interactome is established as a new genome regulatory layer that defines and maintains cellular identity and behavior and is shown to be highly dynamic yet reproducibly organized in cell-type specific networks.

A. Lambolez, P. Sahlén, Wenjing Kang et al. · bioRxiv · 1 citation