Author

M. Bornhäuser

3 papers indexed here

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Open access Sep 2026

Functional characterization of snoRNA-derived RNA (sdRNA) expression in healthy hematopoiesis and acute myeloid leukemia.

SDRNAs are introduced as standalone regulatory effector molecules in healthy hematopoiesis and AML and proposed and characterized NUDT21, an important regulator of alternative polyadenylation and oncogenic gene expression, as a downstream target of sd3'-SNORD78 in AML.

R. Zinz, Christian Rohde, C. Pauli et al. · Leukemia · 0 citations

Open access Aug 2026

Gp120-Activated Allogeneic Regulatory T cells for Prevention of Graft-versus-Host-Disease - a First-in-Human Trial.

BACKGROUND Acute graft-versus-host disease (aGvHD) remains a major complication after allogeneic hematopoietic cell transplantation (alloHCT). Adoptive regulatory T-cell (Treg) therapy may suppress alloreactive T-cell responses, but clinical implementation has been limited by donor-specific manufacturing, prolonged ex...

A. Tuettenberg, L. Ruhnke, J. Schlöder et al. · Transplantation and Cellular... · 0 citations

Editorial Open access Jul 2026

The German National Strategy for Gene- and Cell-Based Therapies: Generating Impact by Employing a Novel Multi-Stakeholder Approach

The main goal of the German National Strategy for GCT is to ensure patient access to advanced therapies while strengthening Germany’s position as an international hub for biomedical innovation.

Christian Gallus, F. Ayuk, P. Beckhove et al. · Human Gene Therapy · 0 citations