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M. Bossi

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Open access Nov 2026

Early hyperactivation and activation-associated mitochondrial abnormalities in GATA2 deficiency

Germline GATA2 deficiency is a hereditary disorder characterized by immunodeficiency, bone marrow failure, and a high risk of myelodysplastic neoplasms and acute myeloid leukemia (AML). Although abnormalities of innate immunity are well recognized, the phenotype and functional state of CD8 + T cells remain inco...

Marta Penco, M. Capelletti, Lorenzo Manfreda et al. · 0 citations

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