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M. Braskie

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Open access Oct 2026

Insulin resistance–related metabolic burden, white matter microstructure, and cognitive change: the HABS-HD study

Background Insulin resistance–related metabolic burden is associated with cognitive aging, but the relevant white matter microstructural features remain unclear. We examined statistical indirect associations between metabolic indices and cognition through tract-level white matter measures, including associations with s...

Huai-Yi Li, Zhi-Liang Tian, Xiao-Qian Wang et al. · 0 citations
Open access Aug 2026

Diabetes and neurodegeneration in cognitively unimpaired older adults: implications for cognition.

Diabetes-related cortical thinning in cognitively unimpaired older adults follows a regional pattern independent of Alzheimer's and cerebrovascular pathology and partially mediates accelerated decline in processing speed, suggesting chronic hyperglycemia may contribute to diabetes-related neurodegeneration, regardless...

A. Tsiknia, Victoria R. Tennant, Marylan Davison et al. · 1 citation
Open access Jul 2026

Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.

A double-cutoff analysis suggest that scans in the 11 to 26 Centiloid range should be interpreted with caution depending on the context of use, and positivity cutoffs converged around 18 Centiloids (data-driven) and 27 Centiloids (visual reads).

G. Blazhenets, D. Soleimani-Meigooni, Konstantinos Chiotis et al. · 5 citations

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