Associations of Angiotensin-Converting Enzyme 2 Activity With Markers of Endothelial Dysfunction and Oxidative Stress in Young Healthy Adults: The African-PREDICT Study.
BACKGROUND Activation of the renin-angiotensin-aldosterone-system plays a major role in the pathogenesis of cardiovascular disease through, among others, endothelial dysfunction and oxidative stress. Circulating ACE2 (angiotensin-converting enzyme 2) is emerging as a biomarker of cardiovascular disease risk; however, i...