Protocol for the Assessment of Endogenous Platelet-Associated Tissue Factor-Dependent Thrombin Generation in Human Platelets Using the Calibrated Automated Thrombogram.
Platelet-associated Tissue Factor (TF) is increasingly recognized as a functionally active determinant of platelet procoagulant activity, enabling platelets to initiate and sustain thrombin generation beyond their established role as a phospholipid surface for coagulation factor assembly. However, its specific function...