Ulcerative colitis is a chronic inflammatory disease of the large intestine, involving flare-ups and remissions. Its exact causes are unclear, but genetic susceptibility, immune dysregulation and environmental influences promote development. Conventional treatments have improved management, but some patients only respo...
C. Caputo, Azzurra Chiara De Maio, Angela Lombardi et al.· Biomedicine & pharmacotherap...· 0 citations
This review provides a comprehensive, updated, and comparative overview of PIK3CA biology, its molecular alterations across human cancers, their prognostic and therapeutic relevance, and the current development of treatments targeting the pathway activated by PIK3CA.
A. Ottaiano, C. Picone, M. Santorsola et al.· Cancers· 0 citations
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