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Author

M. Chrysanthou-Piterou

2 papers indexed here

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Open access Sep 2026

Spatial transcriptomics reveals early and progressive molecular changes in late-onset Pompe disease muscle

Late-onset Pompe disease (LOPD) is caused by acid alpha-glucosidase deficiency, leading to lysosomal glycogen accumulation and progressive muscle pathology. Muscle biopsies show marked fibre heterogeneity, including non-vacuolated and vacuolated fibres. This study aimed to define transcriptomic alterations across the...

Alexandra Monceau, E. Gallardo, A. Hernández-Laín et al. · 0 citations
Oct 2026

Evidence of a redox-dependent regulation of satellite cell activity and regeneration in human skeletal muscle following aseptic injury: a randomized controlled trial.

Satellite cells are essential for skeletal muscle regeneration, with their activity tightly regulated by glutathione (GSH) metabolism and redox balance. Effective regeneration requires an optimal redox hormetic range and balanced GSH levels, as both oxidative and reductive distress can impair redox signaling, satellite...

Konstantinos Papanikolaou, A. Jamurtas, D. Draganidis et al. · 0 citations

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