Author

M. Coyne

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Open access Sep 2026

Host genetics determines the fate of the Lactobacillaceae population in the small intestine

It is found that C57BL/6J (B6) mice harbored significantly more intestinal ASF361 (or other Lactobacillaceae genera) than did BALB/cJ (BALB/c) mice, and such variation should be considered when evaluating probiotic strains and microbiota transplantation.

Helen Beilinson Lietuvninkas, M. Coyne, Kiera Bass et al. · bioRxiv · 0 citations

Open access Jul 2026

Distribution of luxS and production of autoinducer-2 among gut Bacteroidales

It is found that prevalent and abundant human gut Bacteroidales species including Bacteroides uniformis and Phocaeicola vulgatus produce substantial amounts of AI-2, one of two pathways to complete the activated methyl cycle, one that produces the QS molecule AI-2.

Nolan W. Kennedy, R. H. Gellman, M. Coyne et al. · bioRxiv · 0 citations