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Author

M. Cuccaro

3 papers indexed here

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Open access Sep 2026

Heritability and rare variant contributions to Alzheimer disease in the Midwestern Amish

Background The genetic architecture of Alzheimer disease remains incompletely understood. Founder populations such as the Amish offer a unique opportunity to identify additional genetic variation influencing the disease. Method Using extensive pedigree and genomic data from Midwestern Amish communities, we estimated bo...

Yi-Ning Liu, Yeunjoo E. Song, Wei-Huan Wang et al. · 0 citations
Open access Aug 2026

Methylation clocks fail to generalize across genetically admixed individuals

Epigenetic aging clocks based on DNA methylation patterns across the genome have emerged as a potential biomarker for risk of age-related diseases, like Alzheimer’s disease (AD), and environmental and social stressors. However, methylation clocks have not been comprehensively validated in genetically diverse individual...

Sebastián Cruz-González, Ogechukwu Okpala, Esther Gu et al. · 0 citations

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