Author

M. D. de Leon

2 papers indexed here

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Open access Sep 2026

CSF proteomics and machine learning reveal distinct stages across the Alzheimer’s disease continuum

These findings uncover protein signatures that reflect underlying AD biology and provide a foundation for stage-specific biomarkers and therapeutic targeting, with important implications for patient stratification and personalized intervention strategies.

Saima Rathore, E. Dammer, Anantharaman Shantaraman et al. · Molecular Neurodegeneration · 0 citations

Open access Aug 2026

CSF fibrinogen predicts longitudinal Tau accumulation in cognitively unimpaired older adults

Blood–brain barrier (BBB) dysfunction is an early feature of Alzheimer's disease (AD). Fibrinogen represents a sensitive marker of BBB leakage, but whether it modifies longitudinal tau progression in cognitively unimpaired (CU) individuals remains unknown.

C. Lisgaras, Tovia Jacobs, L. Figueredo et al. · Alzheimer's & Dementia · 0 citations