Review
Open access
Oct 2026
The NLRP3 Inflammasome Across the AKI–AKD–CKD Continuum: Mitochondrial, Epigenetic and Endocrine–Metabolic Regulation
The NLRP3 inflammasome has emerged as a potential molecular link between cellular stress, sterile inflammation, and progressive kidney damage. This review critically examines canonical, non-canonical, and mitochondrial mechanisms of NLRP3 regulation across the acute kidney injury (AKI)–acute kidney disease (AKD)–chroni...
D. La Russa, S. Bossio, A. La Russa et al.
· International Journal of Mol... · 0 citations