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M. E. Mancuso

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Open access Oct 2026

CO-57 | NXT007 PROPHYLAXIS IN PEOPLE WITH HEMOPHILIA A WITH OR WITHOUT FACTOR VIII INHIBITORS: COMBINED ANALYSIS OF TWO PHASE I/II MULTIPLE-ASCENDING-DOSE STUDIES

Background. NXT007, a next-generation bispecific antibody based on emicizumab that mimics activated factor (F)VIII function in people with hemophilia A (HA), was investigated in two Phase I/II, open-label, non-randomized, multicenter, multiple-ascending-dose (MAD) studies: one in Asia (NXTAGE Part B; jRCT2080224835) an...

M. E. Mancuso · 0 citations

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