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Open access Oct 2026

Impact of higher comorbidity burden on guideline-directed medical therapy in patients with heart failure with reduced ejection fraction

Patients with a higher comorbidity burden less often used quadruple therapy and had a worse prognosis, as well as its association with clinical outcomes, according to a prespecified subanalysis of the TITRATE-HF registry.

J. J. N. Krabbe, M. I. Wilde, A. Mosterd et al. · 0 citations

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