Author

M. Eslami-Jouybari

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2026

Modulation of CCL5 and CXCR4 as EMT signaling biomarkers by cold atmospheric plasma and Anti-PD-1 combination therapy in melanoma: Insights from integrated bioinformatics and in vitro and in vivo validation

Objective(s): Cold atmospheric plasma (CAP) has emerged as a promising non-thermal modality with anticancer effects. Combining CAP with immune checkpoint blockade (ICB) may enhance therapeutic efficacy, yet the molecular targets underlying this synergy remain incompletely understood. Materials and Methods: Epithelial--...

Zeinab Rostami, F. Akhoundi, Zahra Yazdani et al. · Iranian Journal of Basic Med... · 0 citations

Open access Jul 2026

Altered expression of ET-1 and HMGB1 together with higher MMP-9 activity in serum-derived exosomes of chronic lymphocytic leukemia.

Findings showed that serum-derived exosomes from CLL patients have higher expression of ET-1 and HMGB1 and higher MMP-9 enzymatic activity, which suggest that exosomal ET-1, HMGB1, and MMP-9 may serve as potential non-invasive biomarkers for disease monitoring and warrant further investigation regarding their biologica...

Maryam Ghotbbahaei, Amirhossein Amoei, Maryam Lotfi et al. · Cancer Treatment and Researc... · 0 citations