Author

M. Ezhov

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Open access Sep 2026

Nutraceuticals are a bridge between non-drug and drug-based approaches to the correction of hypercholesterolemia and the prevention of cardiovascular diseases

The burden of lipid metabolism disorders is significant and high. According to the ESSE-RF 3 population-based study conducted in 15 regions of the Russian Federation from 2020 to 2022, which included 28,731 men and women aged 35‒74 years, the prevalence of hypercholesterolemia was 58.8%, and only 7.6% were receiving li...

T. Kolmakova, M. Ezhov · Meditsinskiy sovet = Medical... · 0 citations

Open access Aug 2026

Insights from GWAS, TWAS, and DEG analysis: CDKN2B-AS1, MAP3K4, and P2RX2-encoded P2X2 receptor identified as potential therapeutic targets for ischemic heart disease in Russian adults and long-living individuals

Background The purpose of this study was to investigate genetic risk factors associated with ischemic heart disease (IHD) in Russian adults, to develop prognostic PRS models for IHD risk stratification, and to gain a better understanding of molecular mechanisms underlying IHD through a transcriptome analysis. Materials...

Veronika Daniel, Наталья Георгиевна Романова, A. Mamchur et al. · Frontiers in Cardiovascular... · 0 citations