Author

M. Fascione

3 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Sep 2026

Characterisation of prostate cancer sialome re-engineering via CMAH transfection reveals a bystander effect that propagates Neu5Gc presentation to neighbouring cells

Sialic acids are a family of nine-carbon α-keto sugars that play essential roles in human health and disease. In mammals, they are found in two main forms: N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc), with interactions between Neu5Ac-containing glycans and Siglec receptors on immune cells in...

Yumiko Uno, Amanda R. Noble, Esme Hutton et al. · bioRxiv · 0 citations

Open access Aug 2026

Structural basis for covalent inhibition of sulfatases by sulfamate warheads

The enzymatic removal of sulfate groups regulates processes ranging from steroid metabolism to carbohydrate degradation. Most sulfatases belong to the S1 family, whose members use a co-translationally installed formylglycine residue to hydrolyse sulfate esters. Arylsulfamates are potent covalent inhibitors of aryl and...

C. Tomlinson, Stefano Elli, Morgan Batiste-Simms et al. · bioRxiv · 0 citations

Open access Aug 2026

Lipopolysaccharide insertion and vesicle mediated turnover drive growth independent outer membrane adaptation in Escherichia coli

The Gram-negative outer membrane is a load-bearing permeability barrier dependent on ordered lipopolysaccharide (LPS) packing in its outer leaflet. How this organisation is maintained after LPS insertion, and whether bacteria can remodel LPS independently of growth, remain unclear. Existing models attribute LPS turnove...

Joe Nabarro, Natasha E. Hatton, Bartosz Kowalski et al. · Nature Communications · 0 citations