2,4,5-trimethoxy-2′-trifluoromethylchalcone Attenuates Oxidative Stress and Inflammasome-Associated Inflammation in Experimental Models of Crystal-Induced Inflammation
Crystal-induced arthropathies, including gout and calcium pyrophosphate deposition disease, are characterized by activation of inflammatory and oxidative pathways involving nuclear factor-kappa B (NF-κB) signaling, inflammasome activation, and reactive oxygen species (ROS) generation. This study evaluated the anti-infl...