Design and synthesis of reagents for generation and characterization of high-affinity antibodies for a Staphylococcus aureus serotype 8 disaccharide.
Staphylococcus aureus is a common, opportunistic pathogen, and drug resistance of this organism continues to rise. Substantial efforts have been made to generate vaccines that provide long-lasting protection; however, these have fallen short. High-affinity antibodies could represent a useful treatment modality, taking...