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Author

M. Franchini

1 paper indexed here

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Sep 2026

Abstract B025: A spatial proximity-weighted algorithm (SPAN) defines reproducible tumor niches and a persister ecosystem underlying acquired resistance to pan-RAS inhibition in PDAC

Spatial transcriptomics extends single-cell analysis of the tumor microenvironment into a mappable ecosystem by resolving gene expression in situ. Within it, cells assemble into recurrent multicellular niches whose spatial organization shapes tumor progression, immune evasion, and therapy response and resistance. Yet...

Álvaro Curiel-García, M. Franchini, L. Tomassoni et al. · 0 citations

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