Synthesis of Novel Pyrazolopyranopyrimidine Acyclic Nucleosides Disubstituted at N2/C5 as Potential Anti-SARS-CoV-2 Inhibitors: Structural Characterization, and In Silico Studies
Novel pyrazolo[4′,3′:5,6]pyrano[2,3-d]pyrimidine acyclonucleosides bearing HBG-derived pseudosugar moieties bearing HBG-derived pseudosugar moieties as potential antiviral agents targeting key SARS-CoV-2 proteins are designed and synthesized.